April 19, 2022
- Florida Panthers @ New York Islanders
- Columbus Blue Jackets @ San Jose Sharks
- Minnesota Wild @ Montréal Canadiens
- Calgary Flames @ Nashville Predators
- Winnipeg Jets @ New York Rangers
- Boston Bruins @ St. Louis Blues
- Detroit Red Wings @ Tampa Bay Lightning
- Philadelphia Flyers @ Toronto Maple Leafs
- Ottawa Senators @ Vancouver Canucks
- Los Angeles Kings @ Anaheim Ducks
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