April 16, 2022
- Columbus Blue Jackets @ Los Angeles Kings
- Philadelphia Flyers @ Buffalo Sabres
- San Jose Sharks @ Dallas Stars
- Washington Capitals @ Montréal Canadiens
- Toronto Maple Leafs @ Ottawa Senators
- New Jersey Devils @ Seattle Kraken
- Vegas Golden Knights @ Edmonton Oilers
- Minnesota Wild @ St. Louis Blues
- Pittsburgh Penguins @ Boston Bruins
- Chicago Blackhawks @ Nashville Predators
- Arizona Coyotes @ Calgary Flames
- Carolina Hurricanes @ Colorado Avalanche
- Winnipeg Jets @ Tampa Bay Lightning
- Detroit Red Wings @ New York Rangers
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