April 7, 2022
- Buffalo Sabres @ Carolina Hurricanes
- Seattle Kraken @ Chicago Blackhawks
- Toronto Maple Leafs @ Dallas Stars
- Edmonton Oilers @ Los Angeles Kings
- Calgary Flames @ San Jose Sharks
- Vancouver Canucks @ Arizona Coyotes
- Philadelphia Flyers @ Columbus Blue Jackets
- Montréal Canadiens @ New Jersey Devils
- Pittsburgh Penguins @ New York Rangers
- Nashville Predators @ Ottawa Senators
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